1608. Michelangelo Merisi da Caravaggio, the greatest Italian painter of his day, is expelled from the Order of the Knights of Malta. Subject to a clandestine hearing, his crime remains a closely guarded secret.

2014. Two bodies are found in a London art gallery - stripped naked, necks bound with wire and legs obscenely contorted. They are twin brothers - successful art dealers - their brutal murder linked to the mysterious disappearance of two paintings by the master Caravaggio.

Investigators are confounded, and it falls to art expert Gil Eckhart to identify the killer before he slays again. But as the search for clues takes him from the glamorous skyline of New York to the fetid catacombs of Palermo, Eckhart finds that in the high-stakes world of art, good and evil are often tarred with the same, blood-soaked, brush.